منابع مشابه
A rapid whole blood solubility test to differentiate the sickle-cell trait from sickle-cell anaemia.
A simple and rapid screening test which differentiates sickle-cell trait and sickle-cell anaemia is described. The test utilizes 0.1 ml of whole blood and is based on the low solubility of reduced sickle haemoglobin. Results intermediate between the sickle-cell trait and sickle-cell anaemia are obtained in unusual cases of sickle-cell anaemia with high foetal haemoglobin. The need to supplement...
متن کاملRed blood cell lactate transport in sickle disease and sickle cell trait.
This study determined and compared rates and mechanisms of lactate transport in red blood cells (RBCs) of persons with 1) sickle cell disease (HbSS), 2) sickle cell trait (HbAS), and 3) a control group (HbAA). Blood samples were drawn from 30 African-American volunteers (10 HbSS, 10 HbAS, 10 HbAA). Lactate influx into RBCs was measured by using [14C]lactate at six (2, 5, 10, 15, 25, and 40 mM) ...
متن کاملSickle cell trait.
Sickle cell trait can pose a grave risk for some athletes. In the past few years, exertional sickling has killed nine athletes, including five college football players in training. Exercise-physiology research shows how and why sickle red cells can accumulate in the bloodstream during intense exercise bouts. Sickle cells can "logjam" blood vessels and lead to collapse from ischemic rhabdomyolys...
متن کاملThe sickle cell trait in Jamaica.
J A? IAI(’A, the largest of the British West Indian islands, was originally inhahitated by primitive Amerindians know’n as Arawaks, who dwindled to insignificatit numbers during the one hutidred and sixty-one years of Spanish rule which follow-ed the discovery of the Island in 1494. During the 17th atid 18th centuries, the British and Spanish planters, w-ho had originally settled Jamaica, impor...
متن کاملPre-marriage Sickle Cell Screening Program in South Region of Iran, A Pilot Study on 50 Cases of Sickle Trait
Background: Studies have demonstrated that sickle cell trait can be found in an asymptomatic healthy carrier with normal complete blood count (CBC) and red blood cell (RBC) indices. According to Iranian Ministry of Health bulletin instructions, prenuptial Thalassemia Screening Program (TSP) primarily depends on RBC indices which are measured through a routine CBC. Only when these levels are bel...
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ژورنال
عنوان ژورنال: The Journal of Applied Laboratory Medicine: An AACC Publication
سال: 2017
ISSN: 2475-7241
DOI: 10.1373/jalm.2016.022608